Aseptic technique must always be applied. Apply a generous amount of Celox to the bleeding site (see instructions for use on the package insert) and apply compression until haemostasis is achieved. After haemostasis is achieved, Celox should be removed from the site by irrigation and/or aspiration. Opened packages should not be used.

• It is sufficient to open the package, pour it on the trauma area and make a tampon with gauze.
• The packaging is easy to open.
• One can apply it comfortably to oneself.
• The wound can be easily cleaned.

• CELOX is poured into the bleeding area.
• Coagulation is provided by compressing the area with sterile gauze.
• The gelled clot is easily removed with saline.

Celox particles have a hydraulic molecular structure that provides natural haemostasis by condensing the organelles in the blood (platelets, erythrocytes and blood proteins) to form a gel-like matrix on the surface. The matrix formed by the condensed gel form forms a barrier preventing further blood loss and ensures haemostasis even in the presence of anti-coagulants (heparin sodium, warferin sodium, coumadin, aspirin, etc.). Celox cross-links with minus charged erythrocyte cells with its cationic molecular structure. The concentration of clotting factors, cross-linked red blood cells and activated platelets due to the hydrophilic property of Celox makes coagulation strong. After haemostasis is achieved, it is recommended to remove Celox from the wound using sterile water or saline.

Celox is not intended to replace precise surgical techniques, appropriate ligature applications or conventional haemostasis techniques.